An air strike killed at least 12 children in a Syrian rebel-held town in Aleppo province on Monday when it struck a school, the Syrian Observatory for Human Rights reported.
The air strike on the town of Ain Jara, nearly 10 miles west of Aleppo city, also killed a teacher, and there were reports of others wounded, some of whom were in critical condition, it said.
Social media footage released by activists showed large scale destruction of a building with a classroom with destroyed benches and textbooks lying on the floor stained with blood. The footage could not be independently verified by Reuters.
Meanwhile, Russian news agencies quoted the Russian defense ministry as saying that Russian air force jets have, since the start of 2016, flown 311 combat sorties in Syria and attacked 1,097 terrorist targets there.
Defense ministry official Lieutenant-General Sergei Rudskoy said the targets included oil infrastructure, military equipment and troops under the control of armed terrorist groups, RIA news agency reported.